Variant Effects Seminar Series (VESS)

Pankhuri Gupta is a Research Genetic Counselor at the University of Washington (UW) with experience in variant interpretation, long-read sequencing, and translational genomic medicine. In her current role, she leads efforts to reclassify variants of uncertain significance within the Brotman Baty Institute Clinical Variant Database, which includes clinical genetic data from UW and Fred Hutch patients. She also curates functional datasets and develops training modules on the use of functional evidence.

Pankhuri, alongside her colleagues at the University of Washington including Dr. Abbye McEwen, has organized various workshops on applying functional data in variant classification and has delivered lectures on variant classification for genetic counseling graduate students.

Abbye Elizabeth McEwen, MD, PhD, is a board-certified Molecular Genetic Pathologist and functional genomics researcher based in Seattle, Washington. She completed her MD/PhD at Northwestern, and her pathology residency and Molecular Genetic Pathology fellowship at UW, where she spent four years as an attending physician on the Clinical Exome Service. Her research focuses on bringing multiplexed assay of variant effect data into clinical variant classification.