Workstreams

Alliance Workstreams are responsible for realizing the goals of the Alliance in key areas by setting standards, providing tools and disseminating information.

Experimental Technology and Standards (ETS)

This workstream facilitates the development, scaling, evaluation, comparison and dissemination of new experimental MAVE methods.

Analysis, Modelling and Prediction (AMP)

The AMP workstream drives the development and adoption of computational tools and best practices for analyzing and predicting variant effects from MAVEs and computational models to advance mechanistic and clinical insights.

ClinGen/AVE Functional Data Working Group

This Working Group will focus on approaches for calibration of functional assays for use in variant classification.

Data Coordination and Dissemination (DCD)

The Data Coordination and Dissemination (DCD) workstream facilitates the sharing and discoverability of MAVE projects and MAVE data.