Study Links Genetic Variants to Higher "Bad" Cholesterol and Heart Attack Risk

Date: 30 October 2025

Author: UPMC

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated “bad” cholesterol—a major contributor to heart disease. Published in Science on Oct. 30, 2025, this resource can assist clinicians in predicting patient risk for heart attacks, allowing time for prevention and early treatment.