Season 2 Episode 4: “A series of unfortunate aggregations“ with Drs Benedetta Bolognesi and Ben Lehner

What happens when proteins stop performing their intended function? In the latest episode of the VUS Podcast, the team explore the topic of protein aggregation. Understanding how these aggregates occur can inform strategies to break them apart and may lead to better treatments for the diseases they cause. We hear about the role of deep mutational scanning in helping to understand the biochemistry behind these aggregated proteins and how they can cause disease.

Transcript and show notes

https://zenodo.org/records/23569021