Exploring the landscape of MET kinase domain mutations and inhibitor resistance

Gabriella is a recent alum of the Fraser Lab at UCSF, where she studied the phenotypic and resistance landscape of the MET receptor tyrosine kinase. Her research focused on deciphering kinase domain regulatory motifs and resistance mechanisms to tyrosine kinase inhibitors. Additionally, she studied the relationship between the MET kinase domain and juxtamembrane.