Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements

Florence Chardon

Shendure and Starita Labs, University of Washington

Presentation Date: 6 June 2023

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Florence is a PhD student in the Shendure and Starita labs in the department of Genome Sciences at the University of Washington. After receiving her B.S. in chemistry at UC Berkeley, Florence spent three years at Genentech working in monoclonal antibody therapeutic development before starting graduate school. The focus of her PhD is developing novel multiplex single-cell and bulk functional genomics sequencing-based technologies to study and better understand gene regulatory architecture and the consequences of genetic variation in numerous different in vitro cell culture models. The main application of this work relates to understanding and identifying both proximal and distal regulatory regions that regulate neurodevelopment and autism disorder risk genes with a goal of helping develop gene therapies for these disorders.

Social: @FloChardon